Wine is a major source of polyphenols in the diet, so the characterization and the determination of them in wine samples is a topic of increasing interest with many publications devoted to this issue. Among analytical methods, electroanalyticaltechniques can obtain valuable information, as the antioxidant activity of polyphenols is related to their electrochemical properties. This review examines the potency of electroanalyticaltechniques for the direct evaluation of antioxidant activity and total polyphenol content of wines, and the detection and the quantification of individual polyphenols in these samples. We summarize and critically discuss voltammetric approaches using carbon-based and metallic electrodes and biosensors, and their coupling to flow systems (e.g., flow-injection analysis, high-performance liquid chromatography or capillary electrophoresis) with special attention to contributions from 2000 to date (We recommend that you consult the full text of this article)